Spinach & Artichoke Chicken Bake

Featured in: Weekend Flour-Home Favorites

This comforting one-dish bake features seasoned chicken breasts smothered in a tangy spinach and artichoke topping made with Greek yogurt, mozzarella, and Parmesan cheese. The creamy mixture is sautéed with fresh spinach and artichoke hearts before spreading over the chicken for a 25-30 minute bake until golden and bubbly. Perfect for weeknight dinners, it comes together in just 45 minutes and delivers 48g of protein per serving. Serve alongside rice, quinoa, or a fresh salad for a complete meal.

Updated on Tue, 20 Jan 2026 09:43:00 GMT
The baked spinach and artichoke chicken bake features golden, bubbly cheese topping on tender breasts in a white baking dish. Pin it
The baked spinach and artichoke chicken bake features golden, bubbly cheese topping on tender breasts in a white baking dish. | flourharbor.com

The smell of bubbling cheese and garlic always pulls my husband into the kitchen before dinner is even close to ready. This recipe came from one of those chaotic Tuesday nights when I needed something comforting but didnt have three hours to devote to cooking. Now its the meal my kids actually cheer for when they walk through the door.

Last winter my sister came over after a terrible day at work and I put this in the oven. We stood at the counter picking at the leftover topping while the chicken baked and somehow everything felt less overwhelming. Food has this way of doing that you know

Ingredients

  • Chicken breasts: Boneless skinless breasts work best here but pound them to even thickness so they cook at the same rate
  • Kosher salt and black pepper: Simple seasoning goes a long way since the topping is so flavorful
  • Olive oil: Just enough to sauté the garlic and spinach until fragrant
  • Fresh baby spinach: Wilts down beautifully and adds that gorgeous green color throughout the topping
  • Canned artichoke hearts: Drain them well and give them a rough chop so you get satisfying bites throughout
  • Garlic: Two cloves might seem like a lot but it mellows perfectly when baked
  • Greek yogurt: Use whole milk yogurt if you can find it for the creamiest texture and best flavor
  • Mozzarella and Parmesan: This combo creates that irresistible golden bubbly crust everyone fights over
  • Dried oregano: Adds a subtle earthy note that ties everything together
  • Crushed red pepper flakes: Optional but I love the tiny kick of heat against the rich topping

Instructions

Product image
Whisk eggs, batters, sauces, and cream smoothly for baking, cooking, and everyday meal prep.
Check price on Amazon
Preheat and prep:
Get your oven to 400°F and give a 9x13 baking dish a quick coating of cooking spray or oil
Season the chicken:
Sprinkle both sides of the chicken breasts with salt and pepper then arrange them in your prepared dish without overlapping
Sauté the aromatics:
Warm olive oil in a skillet over medium heat add the garlic and let it sizzle for 30 seconds before tossing in the spinach
Wilt the spinach:
Cook just until the leaves collapse about 2 minutes then remove from heat so they stay vibrant green
Make the topping:
In a bowl mix together the wilted spinach chopped artichokes Greek yogurt mozzarella Parmesan oregano and red pepper flakes until combined
Top and bake:
Spread the mixture generously over each chicken breast then bake for 25 to 30 minutes until the chicken reaches 165°F and the cheese is bubbling and golden
Rest before serving:
Let the dish sit for about 5 minutes so the juices redistribute and the topping sets slightly
Product image
Whisk eggs, batters, sauces, and cream smoothly for baking, cooking, and everyday meal prep.
Check price on Amazon
A close-up view shows the creamy spinach and artichoke chicken bake with herbs and red pepper flakes, perfect for weeknight dinners. Pin it
A close-up view shows the creamy spinach and artichoke chicken bake with herbs and red pepper flakes, perfect for weeknight dinners. | flourharbor.com

This recipe has saved more weeknight dinners than I can count. Theres something about that first forkful of creamy cheesy topping against tender chicken that just works every single time

Making It Your Own

I have played around with this base more than any other recipe in my rotation. Sometimes I swap half the Greek yogurt for cream cheese when I want something extra indulgent. Other times I fold in sun dried tomatoes or sautéed mushrooms depending on what needs using up in the fridge

Side Dish Pairings

The first time I served this with just roasted green beans my husband looked at me like I forgot something. Now I always pair it with something substantial like rice quinoa or even crusty bread to soak up all that creamy topping. A crisp salad on the side helps balance the richness too

Storage and Meal Prep

This recipe has become my go to for Sunday meal prep because it actually reheats beautifully unlike so many chicken dishes. I portion leftovers into glass containers and they are perfect for quick lunches throughout the week

  • Let the dish cool completely before covering and refrigerating
  • Reheat individual portions in the microwave at 50 percent power to prevent the topping from separating
  • The chicken stays moist for up to three days but I doubt it will last that long
Product image
Grill, air fry, roast, and bake perfectly cooked meats and meals indoors with less smoke.
Check price on Amazon
Serve the spinach and artichoke chicken bake alongside a crisp green salad for a high-protein, gluten-free American family meal. Pin it
Serve the spinach and artichoke chicken bake alongside a crisp green salad for a high-protein, gluten-free American family meal. | flourharbor.com

There is nothing quite like pulling this bubbling dish out of the oven and watching everyone gather around the counter. It is simple satisfying food that brings people together exactly what dinner should be

Recipe FAQs

Can I use frozen spinach instead of fresh?

Yes, you can substitute frozen spinach for fresh. Thaw it completely and squeeze out excess moisture before adding to the Greek yogurt mixture to prevent the topping from becoming too watery.

How do I know when the chicken is fully cooked?

The chicken is safely cooked when it reaches an internal temperature of 165°F (74°C) when measured with a meat thermometer in the thickest part. The meat should also be opaque throughout with no pink inside.

Can I prepare this dish ahead of time?

Yes, you can assemble the bake several hours ahead. Cover it with plastic wrap and refrigerate until ready to bake. Add 5-10 minutes to the cooking time if baking from cold.

What sides pair well with this bake?

Rice, quinoa, and roasted vegetables complement this dish nicely. A crisp green salad with lemon vinaigrette or garlic bread also works well to balance the rich, creamy topping.

Is this gluten-free?

Yes, this bake is naturally gluten-free as written. However, always check cheese and yogurt labels for potential cross-contamination if you have gluten sensitivity.

How should I store leftovers?

Store covered leftovers in the refrigerator for up to 3 days. Reheat gently in a 350°F oven for 10-15 minutes until warmed through, or use a microwave for quicker reheating.

Spinach & Artichoke Chicken Bake

Tender chicken breasts baked under a creamy spinach and artichoke topping made with Greek yogurt and cheese.

Prep Time
15 mins
Cook Time
30 mins
Total Duration
45 mins
Created by Brooke Ward


Skill Level Easy

Cuisine American

Makes 4 Portions

Diet Preferences Free from Gluten, Reduced-Carb

Ingredient List

Chicken

01 4 boneless, skinless chicken breasts (approximately 1.5 lbs)
02 0.5 teaspoon kosher salt
03 0.25 teaspoon freshly ground black pepper

Spinach & Artichoke Topping

01 1 tablespoon olive oil
02 2 cups fresh baby spinach, roughly chopped
03 1 can (14 oz) artichoke hearts, drained and coarsely chopped
04 2 cloves garlic, minced
05 1 cup plain Greek yogurt (whole milk preferred)
06 0.5 cup shredded mozzarella cheese
07 0.25 cup grated Parmesan cheese
08 0.25 teaspoon dried oregano
09 0.25 teaspoon crushed red pepper flakes (optional)

Directions

Step 01

Prepare Baking Dish and Season Chicken: Preheat oven to 400°F. Lightly grease a 9x13-inch baking dish. Season chicken breasts with salt and pepper, then arrange in a single layer in the prepared dish.

Step 02

Sauté Aromatics and Spinach: Heat olive oil in a skillet over medium heat. Add minced garlic and sauté for 30 seconds until fragrant. Add chopped spinach and cook until just wilted, approximately 2 minutes.

Step 03

Combine Topping Mixture: In a mixing bowl, combine sautéed spinach, chopped artichoke hearts, Greek yogurt, mozzarella, Parmesan, oregano, and red pepper flakes if using. Mix until well combined.

Step 04

Apply Topping to Chicken: Spread the spinach and artichoke mixture evenly over each chicken breast, covering completely.

Step 05

Bake Until Cooked Through: Bake for 25 to 30 minutes until chicken reaches an internal temperature of 165°F and the topping is golden and bubbly.

Step 06

Rest and Serve: Remove from oven and allow to rest for 5 minutes before serving.

Equipment Needed

  • 9x13-inch baking dish
  • Skillet
  • Mixing bowl
  • Knife and chopping board
  • Measuring cups and spoons

Allergy Details

Read each ingredient label for allergens and talk to a healthcare provider if unsure.
  • Contains dairy (Greek yogurt, mozzarella, Parmesan)
  • May contain eggs if using egg-enriched cheese varieties
  • Verify all ingredient labels for gluten cross-contamination if sensitive

Nutrition info (per serving)

Nutrition stats are for reference and don't serve as medical advice.
  • Calories: 325
  • Fat Content: 11 g
  • Carbohydrates: 7 g
  • Protein: 48 g