Creamy Cajun Chicken Pasta Lite

Featured in: Light Bakes, Breads & Treats

Creamy Cajun Chicken Pasta Lite brings the bold flavors of Louisiana to your table without the guilt. Tender chicken strips and perfectly cooked penne are tossed in a luscious Cajun-spiced sauce made with reduced-fat cream cheese and low-fat milk. Fresh bell peppers, onions, and garlic add vibrant color and flavor, while a touch of lemon brightens every bite. This 40-minute dish delivers restaurant-quality taste with just 420 calories per serving, making it ideal for those seeking healthier comfort food.

Updated on Tue, 20 Jan 2026 08:11:00 GMT
Creamy Cajun Chicken Pasta Lite served in a white bowl with steaming penne, colorful bell peppers, and fresh parsley garnish. Pin it
Creamy Cajun Chicken Pasta Lite served in a white bowl with steaming penne, colorful bell peppers, and fresh parsley garnish. | flourharbor.com

The first time I made this lighter version, my husband actually stopped mid-bite and asked if I was sure this was supposed to be "healthy" pasta. That velvety Cajun sauce clinging to every penne tube fooled us completely.

I originally developed this recipe during a January when we wanted restaurant-quality dinners without the post-meal food coma. Now it is in permanent rotation, requested at least twice a month regardless of the season.

Ingredients

  • Whole wheat penne: The nutty flavor stands up beautifully to the bold Cajun spices and provides satisfying fiber
  • Chicken breasts: Slice against the grain for tender strips that cook evenly and stay juicy
  • Cajun seasoning blend: The backbone of this dish, so use a quality brand or make your own with paprika, garlic powder, and cayenne
  • Bell peppers: Red and yellow peppers add sweetness and crunch that balance the heat
  • Reduced-fat cream cheese: Creates an incredibly silky sauce without the heavy cream calorie load
  • Fresh lemon: Both zest and juice cut through the richness and brighten every bite

Instructions

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Get the pasta going:
Boil the penne until just tender, drain, and save that starchy cooking water—it is liquid gold for fixing sauce consistency later.
Season the chicken:
Toss the strips thoroughly with the spice blend so every piece is evenly coated in that gorgeous red dusting.
Sear the chicken:
Let the pieces develop a golden crust in the hot oil, about 4-5 minutes, then remove them before they overcook.
Soften the vegetables:
Sauté the sliced peppers and onion until they start to caramelize slightly, then add the garlic for just 60 seconds so it does not burn.
Build the sauce:
Return the chicken to the pan, lower the heat, and melt the cream cheese into the milk until everything becomes silky smooth.
Bring it together:
Add the Parmesan, lemon zest and juice, then toss in the cooked pasta until every tube is coated in that spicy creamy goodness.
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A skillet of Creamy Cajun Chicken Pasta Lite features golden chicken strips tossed with al dente pasta in a spicy, creamy sauce. Pin it
A skillet of Creamy Cajun Chicken Pasta Lite features golden chicken strips tossed with al dente pasta in a spicy, creamy sauce. | flourharbor.com

Last winter, my sister declared this her new comfort food after a particularly rough week at work. Sometimes a bowl of pasta is exactly what the soul needs.

Make It Your Own

Shrimp works beautifully here and cooks even faster than the chicken. Just add them during the last 2 minutes of sautéing so they stay tender.

Perfecting the Sauce

Low-fat milk can sometimes break if boiled too aggressively. Keep the heat at medium and stir constantly while the cream cheese melts.

Serving Suggestions

A crisp green salad with vinaigrette cuts through the creaminess perfectly. For a complete meal, add steamed broccoli on the side.

  • Sprinkle extra Parmesan at the table for the cheese lovers
  • Keep red pepper flakes handy for heat seekers
  • Crusty bread is practically mandatory for sopping up sauce
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Garnished with lemon zest and parsley, this Creamy Cajun Chicken Pasta Lite offers a vibrant, lower-calorie meal for weeknight dinners. Pin it
Garnished with lemon zest and parsley, this Creamy Cajun Chicken Pasta Lite offers a vibrant, lower-calorie meal for weeknight dinners. | flourharbor.com

This pasta has saved countless weeknights when we wanted something special but had zero energy for complicated cooking.

Recipe FAQs

Can I use a different pasta shape?

Absolutely. Fettuccine, rigatoni, or bowtie pasta work wonderfully with this sauce. Choose your preferred texture and shape.

How do I make the sauce less thick?

Add the reserved pasta water gradually while stirring. Start with 1-2 tablespoons and adjust until you reach your desired consistency.

What proteins can I substitute for chicken?

Shrimp, tofu, or turkey breast are excellent alternatives. Adjust cooking times accordingly—shrimp needs only 2-3 minutes per side.

How do I add more spice?

Increase the Cajun seasoning or add a pinch of cayenne pepper to the spice rub. You can also stir in hot sauce to the finished sauce.

Can this be made ahead?

Yes, prepare components separately and store in the fridge for up to 2 days. Combine just before serving for best texture. Reheat gently with a splash of milk.

Is this dish gluten-free?

The whole wheat penne contains gluten. Use gluten-free pasta and verify your Cajun seasoning is certified gluten-free to make this suitable for gluten-free diets.

Creamy Cajun Chicken Pasta Lite

Juicy chicken strips and penne tossed in spicy, creamy Cajun sauce with reduced fat and calories for guilt-free indulgence.

Prep Time
15 mins
Cook Time
25 mins
Total Duration
40 mins
Created by Brooke Ward


Skill Level Easy

Cuisine American (Cajun)

Makes 4 Portions

Diet Preferences None specified

Ingredient List

Pasta

01 10 oz whole wheat penne

Chicken

01 2 large boneless, skinless chicken breasts (about 14 oz), sliced into strips
02 1 tablespoon olive oil
03 1 teaspoon Cajun seasoning
04 1/2 teaspoon smoked paprika
05 1/2 teaspoon garlic powder
06 1/2 teaspoon salt
07 1/4 teaspoon black pepper

Vegetables

01 1 red bell pepper, thinly sliced
02 1 yellow bell pepper, thinly sliced
03 1 small red onion, thinly sliced
04 2 cloves garlic, minced

Sauce

01 2/3 cup reduced-fat cream cheese
02 1/2 cup low-fat milk
03 1/4 cup grated Parmesan cheese
04 Zest and juice of 1/2 lemon
05 1 tablespoon fresh parsley, chopped

Directions

Step 01

Prepare Pasta: Cook penne according to package instructions until al dente. Drain and set aside, reserving 1/4 cup pasta water.

Step 02

Season Chicken: In a medium bowl, toss chicken strips with Cajun seasoning, paprika, garlic powder, salt, and black pepper.

Step 03

Cook Chicken: Heat olive oil in a large skillet over medium-high heat. Add chicken and sauté for 4–5 minutes until golden and cooked through. Remove chicken and set aside.

Step 04

Sauté Vegetables: In the same skillet, add bell peppers and red onion. Sauté for 4–5 minutes until softened. Add minced garlic and cook for 1 minute more.

Step 05

Create Sauce: Lower heat to medium. Return chicken to the skillet. Add cream cheese and milk, stirring until smooth and creamy. If sauce is too thick, add reserved pasta water as needed.

Step 06

Combine and Finish: Stir in Parmesan cheese, lemon zest, and juice. Add cooked penne and toss to combine. Season to taste and garnish with chopped parsley before serving.

Equipment Needed

  • Large pot
  • Large skillet
  • Wooden spoon or spatula
  • Knife and cutting board
  • Measuring cups and spoons

Allergy Details

Read each ingredient label for allergens and talk to a healthcare provider if unsure.
  • Contains milk (cream cheese, Parmesan, milk)
  • Contains wheat (pasta)
  • Verify Cajun seasoning for potential allergens and gluten content

Nutrition info (per serving)

Nutrition stats are for reference and don't serve as medical advice.
  • Calories: 420
  • Fat Content: 10 g
  • Carbohydrates: 52 g
  • Protein: 32 g